French Open results on Wednesday, the fourth day of the 2021 tournament at Roland Garros (x denotes seeding): Men 2nd rd Alexander Zverev (GER x6) bt Roman Safiullin (RUS) 7-6 (7/4), 6-3, 7-6 (7/1) Laslo Djere (SRB) bt Miomir Kecmanovic (SRB) 4-6, 4-6, 6-3, 6-2, 6-3 Kei Nishikori (JPN) bt Karen Khachanov (RUS x23) 4-6, 6-2, 2-6, 6-4, 6-4 Henri Laaksonen (SUI) bt Roberto Bautista Agut (ESP x11) 6-3, 2-6, 6-3, 6-2 Casper Ruud (NOR x15) bt Kamil Majchrzak (POL) 6-3, 6-2, 6-4 Alejandro Davidovich Fokina (ESP) bt Botic van de Zandschulp (NED) 6-4, 6-4, 5-7, 2-6, 6-4 Fabio Fognini (ITA x27) bt Marton Fucsovics (HUN) 7-6 (8/6), 6-1, 6-2 Federico Delbonis (ARG) bt Pablo Andujar (ESP) 4-6, 6-1, 3-6, 6-3, 6-2 Stefanos Tsitsipas (GRE x5) bt Pedro Martínez (ESP) 6-3, 6-4, 6-3 John Isner (USA x31) bt Filip Krajinovic (SRB) 7-6 (8/6), 6-1, 7-6 (7/5) Reilly Opelka (USA x32) bt Jaume Munar (ESP) 6-3, 6-2, 3-6, 7-5 Women 2nd rd Danielle Collins (USA) bt Anhelina Kalinina (UKR) 6-0, 6-2 Elena Vesnina (RUS) bt Petra Kvitova (CZE x11) - walkover Victoria Azarenka (BLR x15) bt Clara Tauson (DEN) 7-5, 6-4 Madison Keys (USA x23) bt Leylah Fernandez (CAN) 6-1, 7-5 Anastasia Pavlyuchenkova (RUS x31) bt Ajla Tomljanovic (AUS) 6-2, 6-3 Tamara Zidansek (SLO) bt Madison Brengle (USA) 6-4, 6-1 Katerina Siniakova (CZE) bt Veronika Kudermetova (RUS x29) 7-6 (9/7), 5-7, 7-5 Sorana Cirstea (ROM) bt Martina Trevisan (ITA) 6-4, 3-6, 6-4 Daria Kasatkina (RUS) bt Belinda Bencic (SUI x10) 6-2, 6-2 Polona Hercog (SLO) bt Caroline Garcia (FRA) 7-5, 6-4 Marketa Vondrousova (CZE x20) bt Harmony Tan (FRA) 6-1, 6-3 Paula Badosa (ESP x33) bt Danka Kovinic (MNE) 6-2, 6-0 Ana Bogdan (ROM) bt Naomi Osaka (JPN x2) - walkover afp